Mederi presents to you:

The

Integrated Pain Management Protocol

Summary

Float Therapy (Sensory Enhancement in Epsom Salt Water)

Frequency: 1–2 sessions per week

Duration: 60 minutes per session

Environment: Water at skin temperature (94–95°F), high Epsom salt concentration (~500–800 lbs), complete darkness and silence

Mechanisms:
1. Reduced sensory input → decreased stress response:
Reducing noise and sound reduces activity in the somatosensory and default mode networks, lowering pain perception and stress-related cortisol levels.
Ref: Feinstein et al., 2018 (PLOS ONE) – fMRI showed significant reductions in activity of brain regions associated with pain and anxiety during float sessions.

2. Endorphin and dopamine release:
Floatation increases natural opioids and dopamine, enhancing mood and dampening pain.
Ref: Kjellgren et al., 2001 (Pain Research & Management) – observed increased wellbeing and reduced pain after float sessions in fibromyalgia patients.

Observed Outcomes:
Reduced fibromyalgia symptoms by up to 30%
Lower cortisol, anxiety, and pain scores
Increased feelings of relaxation and body awareness.

Infrared Sauna Therapy

Frequency: 3–4 times per week

Duration: 20–30 minutes per session

Temperature: 120–140°F (50–60°C), far-infrared preferred

Mechanisms:
1. Vasodilation and improved circulation:
Infrared heat penetrates ~1.5 inches into tissue, increasing local blood flow, oxygenation, and nutrient delivery while removing inflammatory metabolites.
Ref: Beever, 2010 (Canadian Family Physician) – showed cardiovascular and neuromuscular benefits of infrared therapy in chronic conditions.

2. Anti-inflammatory effects:
Reduces pro-inflammatory cytokines like IL-6, CRP, and TNF-α.
Ref: Imamura et al., 2001 (J Cardiol) – repeated sauna use decreased inflammatory markers and improved pain in patients with chronic fatigue and pain syndromes.

3. Heat-induced HSPs (heat shock proteins):
Stimulates cellular repair and regeneration pathways via HSP expression.
Ref: Hargreaves et al., 2004 (Journal of Applied Physiology) – HSPs reduce oxidative damage and enhance recovery in skeletal muscles.

4. Endorphin release and parasympathetic activation:
Heat stress triggers opioid-like peptides and enhances autonomic balance.
Ref: Crinnion, 2011 (Altern Med Rev) – sauna promotes parasympathetic activity, important for pain resilience and healing.

Observed Outcomes:
50%+ reduction in musculoskeletal pain in clinical trials.
Improved sleep, mood, and autonomic regulation.
Safer than traditional saunas for many patients due to lower ambient temperature

Mederi`s Offerings

One Week Pain Management Plan

£250

ONLY £130

Stress Buster

£195

ONLY £120